After receiving her BFA from the Art Center College for Design in Pasadena, Penelope Gottlieb went on to earn her MFA from the University of California in Santa Barbara where she currently lives and works.
 
Gottlieb’s work has been exhibited in numerous galleries and museums including: The LA Louver Gallery, The Gerald Peters Gallery, The Michael Kohn Gallery, The Edward Cella Gallery, Light Box Gallery, The Heather James Gallery, The Page Bond Gallery, Otis Art Institute, The Monterey Museum of Art, The Museum of Contemporary Art Santa Barbara, the Nevada Museum of Art, Krannert Art Museum, The Chicago Botanic Garden, Lotusland, The Whatcome Museum.
 
Her work is included in private and public collections including: Los Angeles County Museum of Art, The Chicago Art Institute, The New-York Historical Society Museum & Library, The National Museum of Wildlife Art, The Whitney Museum of Western Art, The Nevada Museum of Art, The 21c Museum, The Fanny May Corp and The Palm Springs Museum of Art. 
Penelope Gottlieb won an Emmy for Motion Picture Title Design.